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factor ix deficiency :: Article Creator Novo Nordisk Files Long-acting Factor IX For Haemophilia B In US Novo Nordisk has filed its long-acting factor IX, nonacog beta pegol in the US for haemophilia B. Nonacog beta pegol is a glycopegylated recombinant factor IX with a longer half-life, developed for patients with haemophilia B. Novo said that the drug's half-life is five times longer than standard factor IX products, meaning fewer injections are needed. Although Novo has long had a presence in haemophilia, it faces competition in both haemophilia A and B. In haemophilia B, Biogen and Swedish Orphan Biovitrum have Alprolix (coagulation factor IX (recombinant)) approved in the EU and the US. The filing of nonacog beta pegol is based on the results from the PARADIGM clinical trial programme which involved 115 patients with severe or moderately severe haemophilia B. Nonacog beta pegol was found to be efficacious in routine prophylaxis, treat...
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