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A short history of gene therapy

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NMC Guidelines For Competency-Based Training Programme For DM Medical Genetics

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Recent Advances in the Treatment of Sickle Cell Disease

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Solving Sickle Cell

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CRISPR-Cas9 Editing of the HBG1 and HBG2 Promoters to Treat Sickle Cell Disease

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Recent Advances in the Treatment of Sickle Cell Disease

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Solving Sickle Cell

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Recent Advances in the Treatment of Sickle Cell Disease

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Thick blood: Causes, risk factors, symptoms, and treatment

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Advances in pig models of human diseases - Hou - 2022 - Animal Models and Experimental Medicine

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What is otosclerosis? Causes, diagnosis and symptoms - Healthy Hearing

- March 09, 2020

Otosclerosis is a form of hearing loss that occurs due to abnormal bone growth in your middle ear. The presence of this bone disrupts the complex series of energy transformations that ultimately allow us to hear. Otosclerosis and hearing loss Inside the ear, sound waves are converted first to mechanical energy, then to electrical energy, explains Dr. Ana H. Kim, MD, an associate professor of otolaryngology-head and neck surgery at Columbia University Medical Center in New York. As part of that effort, three small bones within your middle ear—the malleus, incus and stapes—vibrate. For people with otosclerosis, the smallest bone in the body, the stapes, gets affixed to the surrounding structure, making it unable to move, explains Dr. Kim. “It’s almost like a stop sign. The energy flow just stops right there,” says Dr. Kim. That is, sound enters the ear, but then the bone growth in the middle ear prevents it from making its way to the inner ear. Otosclerosis...

Thick blood: Causes, risk factors, symptoms, and treatment

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Recent Advances in the Treatment of Sickle Cell Disease

- April 25, 2026

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NMC Guidelines For Competency-Based Training Programme For DM Medical Genetics

- July 18, 2025

coagulation factor deficiency syndrome :: Article Creator Factor VII Deficiency: Its Causes, Symptoms, Treatments, And More - WebMD ‌Factor VII deficiency is a rare genetic disorder. It occurs when your body can't produce enough clotting factor VII, which helps in healing wounds. It can be hereditary or be caused by an underlying medical condition. Factor VII deficiency can result in excessive bleeding due to a wound or surgery. ‌ Here is all you need to know about factor VII deficiency, along with its causes, symptoms, and treatments. ‌Your body produces 20 different clotting or coagulation factors. These are proteins that are produced by your body to heal wounds with blood clots. Factor VII, also called proconvertin, is one such clotting factor produced by the liver. It requires vitamin K for its production. Along with other clotting factors and blood cells, it promotes blood clotting at the site of an injury. It forms normal blood cl...

104 Current & Future Uses of Umbilical Cord Stem Cells (Today in 2025)

- November 15, 2025

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I Am Deeply Traumatized From Hearing My Parents Have Sex as a Kid - Slate

- October 21, 2019

Photo illustration by Slate. Photo by Gudella/iStock/Getty Images Plus. I’m a Straight Guy, but Men’s Locker Rooms Really Turn Me On Do I Have to Tell My Lying Ex I Have an STD? I’m a 30-Year-Old Straight Male Virgin Who’s Never Dated Every Ad on My Computer Is Suddenly Ashley Madison. Is My Husband Cheating? How to Do It is Slate’s sex advice column. Send your questions for Stoya and Rich to howtodoit@slate.com . Dear How to Do It, I seem to be dealing with the trauma of hearing my parents have sex when I was a child. It made me feel dirty, disgusting, disrespected, and violated. I am still dealing with these feelings decades later, and it’s still bothering me. I just want to know, is this common? Why do I feel this way? How can I get over it? The fact that my parents could have done it recently or will do it again in the future makes me so sick and angry. I have spoken to my parents, and they just denied it. They also said I was extremely selfish ...

Rare inherited coagulation and fibrinolytic defects that challenge diagnostic laboratories

- August 29, 2025

diseases caused by chromosomal abnormalities :: Article Creator Model Explains Disorders Caused By Improper Transmission Of Chromosomes Parents of healthy newborns often remark on the miracle of life. The joining of egg and sperm to create such delightful creatures can seem dazzlingly beautiful if the chromosome information from each parent has been translated properly into the embryo and newborn. The darker side is that when extra copies of chromosomes or fewer than the normal 46 (23 from each parent) are present, tragic birth defects can occur. Now, scientists at the University of Georgia have developed a model system for plants and animals that shows the loss of a key structural protein can lead to the premature separation of one DNA copy called a chromatid. The new model shows for the first time that the loss of this protein can lead to aneuploidy—the name given to birth disorders caused by extra or too few chromosomes. Disorders caused by err...